In Virudhunagar Government Medical College, Anatomy, Physiology, Biochemistry, Pathology, Microbiology, Pharmacology, Community Medicine and Forensic Medicine departments are functioning. Laboratories are functioning in the departments of Microbiology, Biochemistry and Pathology. In Forensic Medicine Department, approximately 750 postmortems are performed every year.

In Virudhunagar Government Medical College Hospital, departments such as General Medicine, General Surgery, Paediatrics, Obstetrics & Gynaecology, Orthopaedics, Ophthalmology, ENT, Anaesthesia, Dermatology, Respiratory Medicine, Psychiatry, Radio Diagnosis, Dentistry and Emergency Medicine are functioning. Ten Operation Theatres are available in this hospital. Surgeries for ENT, Eye, Dental, Ortho, Urology, Paediatric, Emergency, Septic, Family Welfare, Gynaec, Caesarian etc. are conducted here effectively.